产品货号：
Z20185
中文名称：
MIP-1 beta/CCL4抗体
英文名称：
Anti-MIP-1 beta/CCL4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MIP-1 beta/CCL4 Antibody |
| 指标别名 | ACT 2;ACT2;CCL4;MIP 1 beta |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | CCL4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rabbit polyclonal CCL4 antibody was raised against a 15 amino acid peptide near the center of human CCL4.The immunogen is located within the first 50 amino acids of CCL4. |
| 计算分子量 | 10kDa |
| 成分 | CCL4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CCL4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CCL4,also known as macrophage inflammatory protein 1-beta (MIP1B),belongs to the intercrine beta (chemokine CC) family.Both CCL4 and the related protein CCL3 participate in the host response to invading bacterial,viral,parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells.While both CCL4 and CCL3 exert similar effects on monocytes,their effect on lymphocytes differ;with CCL4 selectively attracting CD4+ lymphocytes and CCL3 selectively attracting CD8+ lymphocytes.Additionally,both have been shown to be potent chemoattractants for B cells,eosinophils and dendritic cells.The processed form of CCL4 can induce down-modulation of surface expression of the chemokine receptor CCR5,thus inhibiting the CCR5-mediated entry of HIV-1 in T cells. |
| Uniprot ID | P13236 |
| 基因名全称 | Chemokine (C-C motif) ligand 4 |
| 蛋白名全称 | Chemokine (C-C motif) ligand 4 |
| 推荐稀释比 | CCL4 antibody can be used for detection of CCL4 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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